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Membranes (ionic permeability, excitability, control)

Membranes (ionic permeability, excitability, control)

1970

Biophysics

1970

1970

Biophysics

V. 15, № 2, 69-88

V. 15, № 2, 69-88

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doi.org

Abstract

Abstract

АННОТАЦИЯ

АННОТАЦИЯ

The mechanism of ionic permeability of bimolecular phospholipid membranes and the mechanism of changes in this permeability by an electric field are examined. A "construction" of the penetrating ions and a method of obtaining carriers for different ions, including carriers in the presence of which ion transfer can be controlled by the electric field on the membrane, are described. The mechanism of action of uncouplers of oxidative phosphorylation is examined and a method of measuring the electrical potential on membranes of mitochondria and photophosphorylating particles is discussed. The construction of a system carrying electrons in mitochondrial membranes and the transfer of electrons through phospholipid membranes are examined. An hypothesis on the role of membranes in the control system of the cell is described. The mechanism of release of quanta of acetylchOline during synaptic transmission and a method of simulating secretion and other interactions between cell membranes by means of bimolecular phospholipid membranes are examined. 

The mechanism of ionic permeability of bimolecular phospholipid membranes and the mechanism of changes in this permeability by an electric field are examined. A "construction" of the penetrating ions and a method of obtaining carriers for different ions, including carriers in the presence of which ion transfer can be controlled by the electric field on the membrane, are described. The mechanism of action of uncouplers of oxidative phosphorylation is examined and a method of measuring the electrical potential on membranes of mitochondria and photophosphorylating particles is discussed. The construction of a system carrying electrons in mitochondrial membranes and the transfer of electrons through phospholipid membranes are examined. An hypothesis on the role of membranes in the control system of the cell is described. The mechanism of release of quanta of acetylchOline during synaptic transmission and a method of simulating secretion and other interactions between cell membranes by means of bimolecular phospholipid membranes are examined. 

chaimatics

Chaimatics

Discovery of links between the biology, physics and mathematics, and founding a new area of studies focused on computations in living systems are his life achievements. Efim Liberman gave the name of “Chaimatics” to this new area of science

I

DNA is the text of a code written for molecular computers of living cells. The notion of “Text” is intrinsically opposite to a random sequence of symbols, and it can exist only inside the system of language. In this case, it is a genetic language, which is isomorphic to a natural language

II

Computations conducted in a living cell are real physical actions, and free energy and time must be spent for completing them. As all living organisms are comprised of cells, this statement is applicable to any control processes implemented in the biosphere

III

Molecular computations are limited by the microscopic scale of a cell and inevitable impact of the computations on formulation of a problem begin solved. The Chaimatics grew from the recognition of the computation reality as the quantum mechanics grew from the recognition of the measurement reality.

IV

A cell creates а quantum computing tool for solving complex problems. This tool utilizes hypersound quanta, and uses the cell cytoskeleton as the computing environment. In such a computer, a price of elementary computation converges to the physical limit, which is Planck’s constant

Chaimatic's statements are simple, but they require a change in the traditional vision, rooted in scientific practice

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Chapter I

The journey of life in science

chaimatics

хаиматика

хаиматика

Итогом жизни в науке стало установление связей между биологией, физикой, математикой и новая область исследования, посвященная вычислениям в живых системах. Ефим Либерман дал имя новой науке: «Хаиматика»

I

ДНК – это текст программы для молекулярных компьютеров клеток. «Текст» по определению не случайная последовательность знаков и может существовать только внутри языковой системы. В данном случае это генетический язык, изоморфный естественному языку

II

Вычисление в живой клетке является реальным физическим действием и требует затрат свободной энергии и времени. Поскольку все живые организмы состоят из клеток, это относится ко всему управлению, которое осуществляется в биосфере

III

Молекулярные вычисления ограничены микроскопическим объемом клетки и принципиальной возможностью влияния вычисления на условия решаемой задачи: квантовая механика возникла из осознания реальности измерения, Хаиматика - из реальности вычисления

IV

Для решения сложных задач клетка создает устройство квантового вычисления, использующего кванты гиперзвука и клеточный цитоскелет, как вычисляющую среду. Цена вычисления в таком компьютере стремится к физическому пределу – постоянной Планка

Утверждения Хаиматики просты, но они требуют изменения традиционных представлений, принятых в научной практике

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Как все начиналось

хаиматика