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chaimatics
Publications
1975
2022
Efim Liberman toward the comprehension of the phenomenon of life
Biosystems
EN
Biological computation: Biosystems, a special issue
1-1
Biological computation: Biosystems, a special issue
2022
Natural computation and its limits: Efim Liberman at the dawn of a new science
Biosystems
EN
Biological computation: Biosystems, a special issue
1-3
Biological computation: Biosystems, a special issue
2022
Neuron quantum computers and a way to unification of science: A compendium of Efim Liberman's scientific work
Biosystems
EN
Biological computation: Biosystems, a special issue
Key publications
122-133
Biological computation: Biosystems, a special issue
2008
Experimental testing of the role of cytoskeleton in the solution by neurons of problems facing the brain
Biochemistry (Moscow)
RU/EN
Biological computation: Molecular computer
Key publications
479-482
Biological computation: Molecular computer
2001
Problems uniting biology, physics, and mathematics: Ideas of a new science
Biophysics
RU/EN
Biological computation: Molecular computer
Biological computation: Molecular computer
1999
Changes in the neuronal membrane permeability induced by Adenosine 3',5'-cyclophosphate
Biophysics
RU/EN
Biological computation: Molecular computer
Biological computation: Molecular computer
1998
Biological information and laws of nature
BioSystems
EN
Biological computation: Molecular computer
Biological computation: Molecular computer
1997
Biophysical and mathematical principles and biological information
Biophysics
RU/EN
Biological computation: Molecular computer
Biological computation: Molecular computer
1996
Cell molecular computers and biological information as the foundation of nature's laws
BioSystems
EN
Biological computation: Molecular computer
Biological computation: Molecular computer
1995
Molecular quantum computer of neuron
BioSystems
EN
Biological computation: Quantum calculation in living systems
Biological computation: Quantum calculation in living systems
1993
Features of spatial organization of the system changing the neuron membrane permeability in response to cAMP. I. The dependence of the membrane permeability changes on the location of cAMP injection
Biological membranes
RU
Biological computation: Molecular computer
Biological computation: Molecular computer
1993
Features of spatial organization of the system changing the neuron membrane permeability in response to cAMP. II. Computer simulation
Biological membranes
RU
Biological computation: Molecular computer
Biological computation: Molecular computer
1992
An iterative approach to complicated models of intracellular control. Intraneuronal injection of cyclic AMP.
Biological membranes
RU
Biological computation: Molecular computer
Biological computation: Molecular computer
1991
Mechanical influence and cAMP injection evoke the same reaction of neuron ionic channels
FEBS Letters
EN
Biological computation: Molecular computer
Key publications
224-226
Biological computation: Molecular computer
1990
Influence of various protein kinase inhibiitors of the effect of intracellular injection of camp into the edible snail neurone
Biophysics
RU/EN
Biological computation: Molecular computer
Biological computation: Molecular computer
1990
Input and output ionic channels of quantum biocomputer
Biophysics
RU
Key publications
Key publications
132-136
Key publications
1989
Molecular quantum computers
Biophysics
RU
Biological computation: Quantum calculation in living systems
Biological computation: Quantum calculation in living systems
1989
Quantum molecular computer model of the neuron and a pathway to the union of the sciences
Biosystems
EN
Biological computation: Quantum calculation in living systems
Key publications
135-154
Biological computation: Quantum calculation in living systems
1989
The kinetics of the cAMP interaction with protein kinase and the neuronal membrane response to cAMP injection
Biological membranes
RU
Biological computation: Molecular computer
Biological computation: Molecular computer
1988
A model for diffusion of camp molecules
Biological membranes
RU
Biological computation: Molecular computer
Biological computation: Molecular computer
1988
Computer modelling of change in neurone membrane conductivity inducing generator potential
Biophysics
RU/EN
Biological computation: Molecular computer
Biological computation: Molecular computer
1988
Unusual biochemistry of changes in neuron membrane permeability evoked by cAMP
FEBS Letters
RU/EN
Biological computation: Molecular computer
Biological computation: Molecular computer
1987
Computer simulation of the neuron membrane permeability changes induced by cAMP injection
Biological membranes
RU
Biological computation: Molecular computer
Biological computation: Molecular computer
1987
Effect of inhibitors and uncouplers oа oxidative phosphorylation on the action of cAMP
Biophysics
RU/EN
Biological computation: Molecular computer
Biological computation: Molecular computer
1987
Effect of phosphate analogs, arsenate, and vanadate, on the membrane potential of mitochondria
Biological membranes
RU
Electrical energetics of a cell
Electrical energetics of a cell
1987
General principles of the work of the receptors and neurones
Biophysics
RU/EN
Biological computation: Molecular computer
Biological computation: Molecular computer
1987
The effect of electron acceptors of 1,4-naphthoquinone group on respiration and membrane potential of liver mitochondria
Biological membranes
RU
Electrical energetics of a cell
Electrical energetics of a cell
1986
Hexaammineruthenium as an electron donor to mitochondrial cytochrome oxidase: membrane potential generation in the absence of cytochrome c
Biochemistry International
EN
Electrical energetics of a cell
Electrical energetics of a cell
1986
Role of the electromechanical and reaction-diffusion system of intraneuronal information processing in the work of the brain
Biophysics
RU/EN
Biological computation: Quantum calculation in living systems
Biological computation: Quantum calculation in living systems
1986
Role of the electromechanical and reaction-diffusional system in intraneuronal information-processing: Influence of the influx of calcium and intracellular calcium on the effect of cAMP
Biophysics
RU/EN
Biological computation: Quantum calculation in living systems
Biological computation: Quantum calculation in living systems
1985
Intraneurone information processing. Increase in sodium and decrease in potassium permeability on injection of a cyclic nucleotide and mechanical stimulation of the neurone
Biophysics
RU/EN
Biological computation: Molecular computer
Biological computation: Molecular computer
1985
Intraneurone processing of information. Delayed change of the membrane potential after administrations of cyclic nucleotides.
Biophysics
RU/EN
Biological computation: Molecular computer
Biological computation: Molecular computer
1985
Membrane potential generation by cytochrome oxidase in the absence of cytochrome с
Biological membranes
RU
Electrical energetics of a cell
Electrical energetics of a cell
1985
Neuron generator potentials evoked by intracellular injection of cyclic nucleotides and mechanical distension
Brain Research
EN
Biological computation: Molecular computer
Key publications
33-44
Biological computation: Molecular computer
1984
Effect of phosphodiesterase inhibitors on membrane potential and respiration of mitochondria
Biophysics
RU/EN
Electrical energetics of a cell
Electrical energetics of a cell
1984
Localization of a ferricyanide-reactive site of cytochrome b−c₁ complex, possibly of cytochrome b or ubisemiquinone, at the outer face of submitochondrial particles
FEBS Letters
EN
Electrical energetics of a cell
Electrical energetics of a cell
1983
A limiting molecular quantum regulator
Biophysics
RU/EN
Biological computation: Quantum calculation in living systems
Key publications
197-201
Biological computation: Quantum calculation in living systems
1982
Change of mechanical parameters as a possible means for information-processing by the neuron
Biophysics
RU
Biological computation: Molecular computer
Key publications
863-870
Biological computation: Molecular computer
1982
Effect of intracellular cyclic nucleotide injection on ionic current under the voltage clamp condition
Biophysics
RU
Biological computation: Molecular computer
Biological computation: Molecular computer
1982
Microinjection of cyclic nucleotides provides evidence for a diffusional mechanism of intraneuronal control
BioSystems
EN
Biological computation: Molecular computer
Biological computation: Molecular computer
1982
Molecular computing as a link between biological and physical theory
Journal of Theoretical Biology
EN
Biological computation: Molecular computer
Key publications
239-252
Biological computation: Molecular computer
1981
Hypothesis about the role of random connections between the brain nerve cells
Biophysics
RU
Biological computation: Molecular computer
Biological computation: Molecular computer
1981
Proton generator of superhigh frequency
Biophysics
RU
Biological computation: Molecular computer
Biological computation: Molecular computer
1980
Membrane potential and effect of unmixed layer on the synthesis of creatine phosphate by heart mithochondria
Biophysics
EN
Electrical energetics of a cell
Electrical energetics of a cell
1980
Phosphorylation of creatine and the membrane potential of heart mitochondria
Biochemistry
RU
Electrical energetics of a cell
Electrical energetics of a cell
1980
Study of diffusion modeling system of neuron
Biophysics
RU
Biological computation: Quantum calculation in living systems
Biological computation: Quantum calculation in living systems
1979
Analog-digital molecular cell computer
BioSystems
EN
Biological computation: Molecular computer
Biological computation: Molecular computer
1979
Biological physics and the physics of the real world
BioSystems
EN
Biological computation: Molecular computer
Biological computation: Molecular computer
1979
Effect of the synthesis of creatine phosphate on the mitochondrial membrane potential
Biophysics
RU
Electrical energetics of a cell
Electrical energetics of a cell
1978
Bioenergetics and proton-electron systems of membranes
Biophysics
RU/EN
Electrical energetics of a cell
Electrical energetics of a cell
1978
Depolarization of the neural membrane on exposure to cyclic 3',5'-adenosine monophosphate and its possible role in the work of the molecular computer (m.c.) of the neurone
Biophysics
RU/EN
Biological computation: Molecular computer
Biological computation: Molecular computer
1978
Molecular computer. Biological physics and physics of the real world
Biophysics
RU
Biological computation: Molecular computer
Biological computation: Molecular computer
1977
Bioenergetics and proton-electron systems of membranes
Biophysics
RU/EN
Electrical energetics of a cell
Electrical energetics of a cell
1977
Membrane potential difference of subcellular particles - III. Proton channels In oxidative photophosphorylation
Biophysics
RU/EN
Electrical energetics of a cell
Electrical energetics of a cell
1977
Membrane potential difference of subcellular particles - IV. Study of the respiratory chain In a portion from FAD to Cytochrome C by the method of penetrating ions
Biophysics
RU/EN
Electrical energetics of a cell
Electrical energetics of a cell
1977
Potential difference across the membrane of subcellular particles. V. Generation of potential differences by mitochondria and submitochondrial particles under anaerobic conditions
Biophysics
RU/EN
Electrical energetics of a cell
Electrical energetics of a cell
1977
Study of metabolic synapse. II. Comparison of cyclic 3',5' AMP and cyclic 3',5' GMP effects
Biophysics
RU
Biological computation: Molecular computer
Key publications
75-81
Biological computation: Molecular computer
1976
Molecular computer of the cell. IX. On coding principles in intracellular information processing
Biophysics
RU
Biological computation: Molecular computer
Biological computation: Molecular computer
1976
Potential difference across the membrane of subcellular particles. I. Chemiosmotic and chemielectric mechanism of generation
Biophysics
RU
Electrical energetics of a cell
Electrical energetics of a cell
1976
Potential difference across the membrane of subcellular particles. II. The compensative method of measurement
Biophysics
RU
Electrical energetics of a cell
Electrical energetics of a cell
1976
Reconstitution of Biological Molecular generators of electric current. Bacteriorhodopsin.
Journal of Biological Chemistry
EN
Electrical energetics of a cell
Electrical energetics of a cell
1976
Study of the action mechanism of fasciolocides with the help of bimolecular phospolipid membranes
Biophysics
RU
Electrical energetics of a cell
Electrical energetics of a cell
1975
Effect of ultraviolet radiation on membranes containing sterols in solutions of nystatin
Biophysics
EN
Artificial membranes
Artificial membranes
1975
Investigation of the cationic selectivity of bimolecular membranes in the presence of nystatin and amphotericin B
Biophysics
RU/EN
Electrical energetics of a cell
Electrical energetics of a cell
1975
Molecular computer of the cell (MC) - VIII. Possible construction of the molecular memory in biological membranes and the principle of the minimum expenditure of free energy of the recording of information
Biophysics
RU/EN
Biological computation: Molecular computer
Biological computation: Molecular computer
1975
Proton channels and the molecular electrostatic generators
Biophysics
RU/EN
Electrical energetics of a cell
Electrical energetics of a cell
1975
Study of the metabolic synapse - I. Effect of intracellular micro injection of 3',5' - AMP
Biophysics
RU/EN
Biological computation: Molecular computer
Key publications
457-463
Biological computation: Molecular computer
1975
The molecular computer of the cell - VII. Cell biophysics and realistic or informational physics (I).
Biophysics
EN
Biological computation: Molecular computer
Biological computation: Molecular computer
1974
Cell molecular computer. VI. Method of studying the role of a single nerve cell and nerve net in brain functioning
Biophysics
RU
Biological computation: Molecular computer
Biological computation: Molecular computer
1974
Direct measurement of electric current generation by cytochrome oxidase, H⁺-ATPase and bacteriorhodopsin
Nature
EN
Electrical energetics of a cell
Key publications
321-324
Electrical energetics of a cell
1974
Intramembrane electric field and mechanism of hydroxylation
Biophysics
RU/EN
Electrical energetics of a cell
Electrical energetics of a cell
1974
Mechanism of conductivity of bimolecular lipid membranes in the presence of tetrachlorotrifluoromethylbenzimidazole
Journal of Membrane Biology
EN
Electrical energetics of a cell
Electrical energetics of a cell
1974
Molecular computer (m.c.) of the cell - V. Mechanism of the recording of signals arriving at the synapses into codes of the m.c.
Biophysics
RU/EN
Biological computation: Molecular computer
Biological computation: Molecular computer
1974
Permeability of phospholipid membranes for valinomycin
Biophysics
RU/EN
Electrical energetics of a cell
Electrical energetics of a cell
1974
Permeability of spatial and boundary charges of bimolecular phospholipid membranes - I. Distribution coefficient
Biophysics
RU/EN
Electrical energetics of a cell
Electrical energetics of a cell
1974
The cell as a molecular computer (m.c.). IV. "Price of action" as a value characterizing the "difficulty" of solving a problem for a computer device.
Biophysics
RU/EN
Biological computation: Molecular computer
Biological computation: Molecular computer
1973
Interaction of polyenic antibiotic derivatives of amphotericine B with bimolecular membranes
Biophysics
RU
Electrical energetics of a cell
Electrical energetics of a cell
1973
Interaction of the derivatives of the polyene antibiotic amphotericin B with bimolecular membranes
Biophysics
EN
Electrical energetics of a cell
Electrical energetics of a cell
1973
Ionic permeability of bimolecular membranes in the presence of polyene antibiotics. II. Levorine, trychomycine, candycydine
Biophysics
RU
Electrical energetics of a cell
Electrical energetics of a cell
1973
Molecular computer - II. Formal description (system of operation)
Biophysics
RU/EN
Biological computation: Molecular computer
Key publications
1003-1006
Biological computation: Molecular computer
1973
The Cell as a molecular computer (m.c.) - III. Possible design of an "ideal" computer in a liquid membrane
Biophysics
RU/EN
Biological computation: Molecular computer
Biological computation: Molecular computer
1973
Theory of the relaxation current in clamp experiments on the membranes with ion carriers
Biophysics
RU
Electrical energetics of a cell
Electrical energetics of a cell
1972
Absorption of "penetrating" anions by hydrophobic parts of macromolecules
Molecular Biology
RU/EN
Electrical energetics of a cell
Electrical energetics of a cell
1972
Fusion of bimolecular membranes as a model of cell contact
Biophysics
RU
Electrical energetics of a cell
Key publications
Electrical energetics of a cell
1972
Ionic permeability of bimolecular membranes in the presence of polyenic antibiotics. I. Nystatin and amphotericin B
Biophysics
RU
Electrical energetics of a cell
Electrical energetics of a cell
1972
Kinetics of adhesion and surface electroconductance of bimolecular phospholipid membranes
Biophysics
RU
Electrical energetics of a cell
Electrical energetics of a cell
1972
Role of cholesterol in the increase in conductivity of bimolecular membranes by polyene antibiotics
Biophysics
EN
Electrical energetics of a cell
Electrical energetics of a cell
1972
The cell as a molecular computer (m.c.) - I. General ideas and hypotheses
Biophysics
RU/EN
Biological computation: Quantum calculation in living systems
Key publications
979-993
Biological computation: Quantum calculation in living systems
1971
Mobile ion carriers and negative membrane resistance. I. Uncouplers of oxidative phosphorylation - proton carriers
Biophysics
RU
Electrical energetics of a cell
Electrical energetics of a cell
1971
The effect of concentration amplification in artificial phospholipid membranes
Biophysics
RU
Electrical energetics of a cell
Electrical energetics of a cell
1970
Charged and neutral ion carriers through bimolecular phospholipid membranes
Biochimica et Biophysica Acta (BBA) - Biomembranes
EN
Electrical energetics of a cell
Electrical energetics of a cell
1970
Comparison of the properties of biomolecular membranes of phospholipids of brain, mitochondria and bacteria
Biophysics
RU
Electrical energetics of a cell
Electrical energetics of a cell
1970
Conversion of biomembrane-produced energy into electric form. I. Submitochondrial particles
Biochimica et Biophysica Acta (BBA) - Bioenergetics
EN
Electrical energetics of a cell
Key publications
1-12
Electrical energetics of a cell
1970
Conversion of biomembrane-produced energy into electric form. II. Intact mitochondria
Biochimica et Biophysica Acta (BBA) - Bioenergetics
EN
Electrical energetics of a cell
Electrical energetics of a cell
1970
Conversion of biomembrane-produced energy into electric form. III. Chromatophores of Rhodospirillum rubrum
Biochimica et Biophysica Acta (BBA) - Bioenergetics
EN
Electrical energetics of a cell
Key publications
22-29
Electrical energetics of a cell
1970
Conversion of biomembrane-produced energy into electric form. IV. General discussion
Biochimica et Biophysica Acta (BBA) - Bioenergetics
EN
Electrical energetics of a cell
Electrical energetics of a cell
1970
Effect of beryllium ions on end-plate potential and frequency of miniature potentials of the frog myoneural junction
Biophysics
RU/EN
Electrical energetics of a cell
Electrical energetics of a cell
1970
Effect of uncouplers of oxidative phosphorylation on output of acetylcholine from nerve endings
Neuroscience and Behavioral Physiology
RU/EN
Electrical energetics of a cell
Key publications
115-121
Electrical energetics of a cell
1970
Electrooptical phenomena in bimolecular phospholipid membranes
Biochimica et Biophysica Acta (BBA) - Biomembranes
EN
Electrical energetics of a cell
Electrical energetics of a cell
1970
Membranes (ionic permeability, excitability, control)
Biophysics
RU/EN
Electrical energetics of a cell
Electrical energetics of a cell
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chaimatics
Chaimatics
Discovery of links between the biology, physics and mathematics, and founding a new area of studies focused on computations in living systems are his life achievements. Efim Liberman gave the name of “Chaimatics” to this new area of science
I
DNA is the text of a code written for molecular computers of living cells. The notion of “Text” is intrinsically opposite to a random sequence of symbols, and it can exist only inside the system of language. In this case, it is a genetic language, which is isomorphic to a natural language
II
Computations conducted in a living cell are real physical actions, and free energy and time must be spent for completing them. As all living organisms are comprised of cells, this statement is applicable to any control processes implemented in the biosphere
III
Molecular computations are limited by the microscopic scale of a cell and inevitable impact of the computations on formulation of a problem begin solved. The Chaimatics grew from the recognition of the computation reality as the quantum mechanics grew from the recognition of the measurement reality.
IV
A cell creates а quantum computing tool for solving complex problems. This tool utilizes hypersound quanta, and uses the cell cytoskeleton as the computing environment. In such a computer, a price of elementary computation converges to the physical limit, which is Planck’s constant
Chaimatic's statements are simple, but they require a change in the traditional vision, rooted in scientific practice
Read a book
Chapter I
The journey of life in science
chaimatics